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Introduction: Kirk’s Current Veterinary Therapy XV
Getting Started with Kirk’s Current Veterinary Therapy XV, Shock is a state of severe hemodynamic and metabolic derangements. It is characterized by poor tissue perfusion from low or unevenly distributed blood flow that leads to a critical decrease in oxygen delivery (DO2) in relation to oxygen consumption (VO2) (Fig. 1-1) and/or inadequate cellular energy production. If the shock state is not promptly recognized and treated, neurohormonal compensatory mechanisms will lead to stimulation of the renin-angiotensin-aldosterone system, as well as baroreceptor and chemoreceptor-mediated release of catecholamines and subsequent production of counter re-regulatory hormones (glucagon, adrenocorticotropic hormone [ACTH], and cortisol). These changes will increase cardiovascular tone, activate a variety of biochemical mediators, and stimulate inflammatory responses that contribute to the shock syndrome.
This progression can cause or exacerbate uneven microcirculatory flow, poor tissue perfusion, tissue hypoxia, altered cellular metabolism, cellular death, and vital organ dysfunction or failure. Box 1-1 lists the different types of shock, but this classification can be overly simplistic. Critically ill patients are subject to complex etiologic and pathophysiologic events and therefore may suffer from more than one type of shock simultaneously. The rationale for the functional classification of shock is the presumption that each underlying illness identified can be associated with a specific pathophysiologic process and rapid, appropriate therapy can be administered.
Kirk’s Current Veterinary Therapy XV Chapters And Sections
Table Of Contents
Endocrine and Metabolic Diseases
Oncology and Hematology
Neurologic and Musculoskeletal Diseases
Kirk’s Current Veterinary Therapy:
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